专利内容由知识产权出版社提供
专利名称：PREDICTION OF OUTCOME IN PATIENTS
WITH CHRONIC OBSTRUCTIVEPULMONARY DISEASE
发明人：GIERSDORF, Sven,TAMM, Michael,STOLZ,
Daiana
申请号：EP13707113.0申请日：20130226公开号：EP2823314A1公开日：20150114
摘要：The present invention relates to a method for the prognosis and/or risk
assessment and/or monitoring of therapy and/or management of patients with COPD themethod comprising the steps of: i) providing a sample of a bodily fluid from said patient,ii) determining in said sample the level of at least one biomarker, selected from thegroup consisting of pro-adrenomedullin (proADM), pronatriuretic peptide, pro-Vasopressin (proAVP) and Procalcitonin (PCT) or fragments thereof of at least 12 aminoacids in length, iii) determining one, two or three of the BODE-index parameters body-mass index (BMI, parameter B), degree of airflow obstruction (FEV 1 , parameter O),dyspnea (parameter D) and exercise capacity (parameter E), iv) correlating said level ofsaid at least one biomarker determined in step ii), in combination with said one, two orthree BODE-index parameters determined in step iii) to the prognosis and/or riskassessment and/or monitoring of therapy and/or management of patients with COPD.
申请人：B.R.A.H.M.S GmbH
地址：Neuendorfstrasse 25 16761 Hennigsdorf DE
国籍：DE
代理机构：Tomerius, Isabel
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