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专利名称：Substituted 2-imidazolone derivatives, their
preparation and pharmaceuticalcompositions
发明人：Deirdre M. B. Hickey,David G. Cooper,Albert
A. Jaxa-Chamiec
申请号：US08/030094申请日：19930510公开号：US05338752A公开日：19940816
摘要：##STR1## Substituted 4,5-diaryl-2-imidazolones of structure (I) , in which eachgroup AR is the same or different and is optionally substituted phenyl or optionallysubstituted heteroaryl; R.sup.1 is hydrogen, alkyl, optionally substituted phenyl oroptionally substituted heteroaryl; n is 4 to 12; and X is 5-tetrazolyl, SO.sub.3 H, P(O)(OR).sub. 2, P(O)(OH).sub.2 or P(O)(R)(OR) in which R is hydrogen acceptable salt thereof,processes for preparing them, pharmaceutical compositions containing them and theiruse in therapy, inter alia, in the treatment of cardiovascular disorders.
申请人：SK&F LABORATORIES LTD.
代理人：Dara L. Dinner,Stephen Venetianer,Edward T. Lentz
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