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专利名称：Improvement of the efficiency of
pharmaceutical active agent-releasingmedical products through combination withan inhibitor of the P-glycoprotein transportprotein
发明人：GRATZ, MATTHIAS,BORCK, ALEXANDER申请号：EP09174332.8申请日：20091028公开号：EP2186531A2公开日：20100519
摘要：Medical product having a surface coated entirely or partially with a biostableand/or biodegradable polymer layer, is claimed. At least one inhibitor of a transportprotein permeability glycoprotein (P-glycoprotein) and at least one active substance arepresent in and/or on the biostable and/or biodegradable polymer layer. The inhibitor ofthe transport protein P-glycoprotein is PSC833, GF120918, XR9576 (tariquidar), LY335979or OC144-093. Independent claims are also included for producing the medical productcomprising providing PSC833, GF120918, XR9576 (tariquidar), LY335979 or OC144-093 asan inhibitor of the transport protein P-glycoprotein.
申请人：BIOTRONIK VI PATENT AG
地址：Neuhofstrasse 4 6341 Baar CH
国籍：CH
代理机构：Lindner-Vogt, Karin L.
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