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ANTI-CANCER EFFECTS OF PROTEASOME INHIBITORS IN CO

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专利名称:ANTI-CANCER EFFECTS OF PROTEASOME

INHIBITORS IN COMBINATION WITHGLUCOCORTICOIDS, ARSENIC CONTAININGCOMPOUNDS, AND ASCORBIC ACID

发明人:BERENSON, James R.申请号:EP15807258.7申请日:20150610公开号:EP3154596A1公开日:20170419

摘要:The present invention provides methods of treatment for hematologicalmalignancies involving synergistic combination of a proteasome inhibitor, a

glucocorticoid, an arsenic-containing compound, and ascorbic acid or a derivative thereofprovide an unexpected efficacy in the treatment for hematological disorders. Thehematological disorders treated by the current invention include multiple myeloma, andmay also include hematological disorders that are refractory to prior cancer treatments,or relapsed hematologic disorders.

申请人:Institute for Myeloma & Bone Cancer Research

地址:9201 Sunset Boulevard, Suite 300 West Hollywood, CA 90069 US

国籍:US

代理机构:Cooley (UK) LLP

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