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Aza-aryl 1H-pyrazol-1-YL benzene sulfonamides

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专利名称:Aza-aryl 1H-pyrazol-1-YL benzene

sulfonamides

发明人:Xi Chen,Junfa Fan,Pingchen Fan,Antoni

Krasinski,Lianfa Li,Rebecca M. Lui,Jeffrey P.McMahon,Jay P. Powers,Yibin Zeng,PenglieZhang

申请号:US13781412申请日:20130228公开号:US016601B2公开日:20141223

摘要:Compounds are provided that act as potent antagonists of the CCR(9) receptor.Animal testing demonstrates that these compounds are useful for treating inflammation,a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivativesand are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.

申请人:ChemoCentryx, Inc.

地址:Mountain View CA US

国籍:US

代理机构:Brinks Gilson & Lione

代理人:Ryan L. Marshall,William Boudreaux

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